摘要
目的观察动物胃提取物对实验性胃溃疡小鼠模型的保护作用。方法用3种剂量(0.3,0.1,0.03 g/kg)的动物胃提取物及雷尼替丁0.02 g/kg给小鼠灌胃,观察各药对利血平、盐酸、无水乙醇型小鼠胃溃疡模型的影响。结果动物胃提取物能有效抑制利血平、盐酸、无水乙醇型小鼠胃溃疡所致黏膜损伤。结论动物胃提取物有抗实验性小鼠胃溃疡的作用。
Purpose To observe the protective effects of the extract from mammalian stomach on the mice gastric ulcer models. Methods Feeding the mice models with the extract from mammalian stomaeh（0.3,0.1, 0.03g/kg）and ranitidine （0.02 g/kg）, observed the effect of the extract on the gastric ulcer induced by reserpine, hydrochloric acid and ethanol in mice. Results The extract from Mammalian Stomach can prevent the gastric mucosa of mice from suffering gastric ulcer induced by reserpine, hydrochloric acid and ethanol. Conclusion The extract can treat experimental gastric ulcer.
出处
《中国生化药物杂志》
CAS
CSCD
2008年第6期400-402,共3页
Chinese Journal of Biochemical Pharmaceutics
关键词
动物胃提取物
胃溃疡
保护作用
the extract from mammalian stomach
gastric ulcer
protective effects
