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细菌肝素前体(heparosan)合酶 被引量：5

Heparosan synthase of bacteria
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摘要 肝素前体(heparosan)为糖胺聚糖家族一员,是某些细菌产生的荚膜多糖成分,同时也作为动物体内合成肝素、硫酸乙酰肝素的前体物,具有与肝素类似的多糖骨架。细菌heparosan合酶已引起广泛关注,因为此酶的应用可使通过化学或生物修饰生产肝素、硫酸乙酰肝素成为可能。此文对已发现的细菌heparosan合酶系统作一综述。
作者 陈祥娥 凌沛学 张天民
机构地区 山东大学药学院 山东省生物药物研究院博士后科研工作站
出处 《中国生化药物杂志》 CAS CSCD 2008年第6期422-424,共3页 Chinese Journal of Biochemical Pharmaceutics
关键词 heparosan舍酶 肝素 细菌
分类号 Q538 [生物学—生物化学]
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参考文献18

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同被引文献63

  • 1边玲.多糖命名法[J].食品与药品,2010,12(11):455-457. 被引量：1
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  • 7Xiao Z, Theroux P. Platelet activation with unfractionated heparin at the therapeutic concentrations and comparisons with a low-molecular-weight heparin and with a direct thrombin inhibitor[ J ]. Circulation, 1998,97 (3) :251-256.
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二级引证文献3

中国生化药物杂志
2008年 第6期

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