腹膜后良恶性肿瘤的超声造影初步研究

Preliminary study on the retroperitoneal tumors by contrast-enhanced ultrasonography

目的探讨超声造影在腹膜后良恶性肿瘤鉴别诊断中的价值。方法42例腹膜后肿瘤患者，活检或手术前在低机械指数下应用SonoVue进行超声造影，观察良恶性肿瘤的超声造影表现，分析时间-强度曲线（TIC）特征。结果在超声造影下，腹膜后良性肿块可以呈现不同的声像图特征。恶性肿瘤呈现中央向周边的增强模式，增强血管迂曲，并呈现非整体增强，无回声坏死灶多见。TIC曲线中恶性组感兴趣区增强强度（P〈0．001）、上升斜率（P〈0．05）及半降时间（P〈0．05）与良性组差异有统计学意义。结论腹膜后肿瘤具有不同的超声造影表现，有助于良恶性肿瘤的鉴别诊断。

Objective To analyze the blood perfusion characteristics of retroperitoneal benign and malignant tumors hy real-time contrast-enhanced ultrasonography and discuss its value in the differential diagnosis. Methods The study involved 42 patients with pathological evidence through surgery or needle biopsy, including 12 patients with benign retroperitoneal tumors and 30 patients with malignant retroperitoneal tumors. The blood perfusion characteristics of two groups were observed under low mechanical index after the injection of contrast ultrasound agent （SonoVue）, and the changes of twodimensional ultrasonography and the time-intensity curve（TIC） were analyzed. Results During real time contrast enhancement, the different characteristics of retroperitoneal benign and malignant tumors were observed . Malignant tumors in retro peritoneum presented the pattern of ultrasound contrast agent（UCA） enhancement from center to periphery and enhanced overall uneven mainly, begin tumors presented peripheral enhancement pattern or uniformity and overall strengthening of the main. TIC curve between benign and malignant tumors displayed that contrast enhanced intensity of region of interest（ P 〈0. 001）, ascending slop and halftime of descending were statistically significant（ P〈0.05）. Conclusions Real-time contrast-enhanced ultrasonography is a valued method to provide information for the differential diagnosis in retroperitoneal benign and malignant tumors.