期刊文献+

雌激素及其受体与非小细胞肺癌的研究进展 被引量:1

原文传递
导出
摘要 雌激素(E)作为人体内环境调节的主要因素之一,不仅有重要的生理作用,还与某些肿瘤的发生、发展关系密切。最近的研究发现,正常肺组织(E的非靶器官)及非小细胞肺癌(NSCLC)中存在雌激素受体(ER)的两种亚型(ERα和ERβ),E与NSCLC的发生可能有密切关系,对其机制进行深入研究,可能会发现治疗NSCLC的新方法。现就E及其受体与NSCLC的研究现状进行综述如下。
出处 《中华胸心血管外科杂志》 CSCD 北大核心 2008年第6期425-427,共3页 Chinese Journal of Thoracic and Cardiovascular Surgery
  • 相关文献

参考文献28

  • 1Power KA, Thompson LU. Ligand-induced regulation of ERalpha and ERbeta is indicative of human breast cancer cell proliferation. Breast Cancer Res Treat,2003,81:209- 221.
  • 2Bardin A, Hoffmann P, Boulle N, et al. Involvement of estrogen receptor beta in ovarian carcinogenesis. Cancer Res,2004,64:5861 - 5869.
  • 3Howell A, Pippen J, Elledge RM, et al. Fulvestrant versus anastrozole for the treatment of advanced breast carcinoma: a prospectively planned combined sttrvival analysis of two multicenter trials. Cancer, 2005,104: 236 - 239.
  • 4Iavarone M, Lampertico P, Seletti C, et al. The clinical and pathogenetic significance of estrogen receptor-beta expression in chronic liver diseases and liver carcinoma. Cancer,2003,98:529 - 534.
  • 5Takano N, Iizuka N, Hazama S, et al. Expression of estrogen receptor- alpha and -beta mRNAs in human gastric cancer. Cancer Lett,2002,176: 129 - 135.
  • 6Radzikowska E, Glaz P, Roszkowski K. Lung cancer in women: age, smoking, histology, performance status, stage, initial treatment and survival. Population-based study of 20 561 cases. Ann Oncol,2002, 13: 1087 - 1093.
  • 7Henschke CI, Yip R, Miettinen OS. Women's susceptibility to tobacco carcinogens and survival after diagnosis of lung cancer. JAMA,2006,296: 180- 184.
  • 8Liu Y, Inoue M, Sobue T, et al. Reproductive factors, hormone use and the risk of lung cancer among middle-aged never-smoking Japanese women: a large-scale population-based cohort study. Int J Cancer,2005,117: 662 - 666.
  • 9陈东义,胡永校,毕建斌,李玉,韩立波.雌、孕激素受体在非小细胞肺癌组织中的表达及临床意义的研究[J].中国医科大学学报,1998,27(2):161-164. 被引量:19
  • 10周向东,蔡文琴,曹红卫.男性肺癌患者外周血性激素水平及其与肺癌组织中芳香化酶表达的相关性研究[J].癌症,2002,21(3):259-262. 被引量:17

二级参考文献19

  • 1戴旺福,中华肿瘤杂志,1993年,15卷,6期,434页
  • 2Fairlamb D,Boesen E. Gynaecomastia associated with gonadotrophin-secreting carcinoma of the lung [J]. Postgrad Med J, 1977,53(7):269-271.
  • 3刘国龙,盛信秀.性激素与肿瘤[M].见:性激素与老年疾病.吴赛珠.第1版.北京:中国科学技术出版社,1997:199-211.
  • 4Lu Q,Nakmura J,Savinov A,et al. Expression of aromatase protein and messenger ribonucleic acid in tumor epithelial cells and evidence of functional significance of locally produced estrogen in human breast cancers [J]. Endocrinology,1996,137(7):3061-3068.
  • 5Thijssen JH,Daroszewski J,Milewicz A,et al. Local aromatase activity in human breast tissues [J]. J Steroid Biochem Mol Biol,1993,44:577-582.
  • 6Wynder E L. The past, present, and future of the prevention of lung cancer. Cancer Epidemiol Biomark Prev, 1998,7: 735.
  • 7Jiang Y G, Chen J K, Wu Z L. Promotive effect of diethylstilbestrol on urethane-induced mouse lung tumorigenesis. Chemosphere, 2000, 41: 187.
  • 8Stabile L P, Davis A L, Gubish C T et al. Human non-small cell lung tumors and cells derived from normal lung express both estrogen receptor alpha and beta and show biological responses to estrogen. Cancer Res, 2002,62:2141.
  • 9Omoto Y, Kobayashi Y, Nishida K et al. Expression function and clinlcal implications of the ERβ in human lung cancers. Biochem Biophys Res Commun, 2001,285: 340.
  • 10Mollerup S, Jorgensen K, Berge G et al.Expression of estrogen receptors alpha and beta in human lung tissue and cell lines. Lung Cancer, 2002,37:153.

共引文献44

同被引文献20

引证文献1

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部