C-反应蛋白在脑损伤患者表达意义的临床研究

Clinical research about the expression of c-reactive protein in traumatic brain injury

目的:研究脑损伤后患者血清C-反应蛋白(CRP)水平与脑损伤之间的关系。方法:测定114例颅脑损伤患者血清C-反应蛋白,根据格拉斯哥(GCS)评分,分析CRP与轻、中、重、特重型颅脑损伤之间的关系。结果:CRP伤后即升高,达到峰值的时间、升高增加程度及升高持续时间组间存在差异。结论:血清CRP是颅脑损伤患者急性期脑损伤敏感而特异的血清学指标,对伤情判断、治疗效果和预后有临床参考价值。

Objective： To investigate the relationship between dynamic changes of serum CRP and cranioeerebral trauma. Methods： According to the GCS at admission , to analyze the relationship about traumatic brain injury and CRP in 4 groups. Results： The content of serum CRP increased on the first day after injury , there are differences in the time of reaching the top level, increasing degree, persistence time in different group. Conclusion： The serum CRP is valuable for management and prediction of traumatic brain injury.