187例药物不良反应分析报告

Analysis report of 187 cases adverse drug reaction

目的:了解某院药品不良反应(ADR)发生规律。方法:对187例ADR报告,按年龄、性别、用药情况、涉及药品种类、累及器官或系统以及临床表现进行分析。结果:中药注射剂引发ADR比例最高,其次为抗感染药物,静脉给药是引起ADR的主要给药途径,ADR的临床表现以皮疹、瘙痒等皮肤及附件损害最常见。结论:应加强ADR监测,以提高合理用药。

Objective： To study clinical features of adverse drug reaction （ADR） in our hospital. Methods： A total of 187 ADR cases reports collected from July 2007 to June 2008 in our hospital were analyzed statistically in respect of patients, age and sex, drug utilities, drug categories, organs and systems involved and clinical manifestations etc. Results： Of the total ADR cases, 28.34% ADR caused by the traditional Chinese medicine injection, followed by anti-infection drugs, the intravenous medication was the main route of medication resulting in ADR, ADR were mainly manifested as lesions of skin and the appendants. Conclusion： Great importance should be attached to the monitoring of ADR to improve rational drug use level.