龙胆泻肝配方颗粒治疗湿热型生殖器疱疹的临床观察

Curative effects of Longdan Xiegan granule on treatment of damp-heat genital herpes

目的观察龙胆泻肝配方颗粒治疗湿热型生殖器疱疹的临床疗效,比较其与传统汤药及西药阿昔洛韦的临床疗效。方法将60例生殖器疱疹患者随机分为龙胆泻肝配方颗粒组、龙胆泻肝汤方组及西药阿昔洛韦组,观察治疗前后患者临床证候积分,判断其近期临床疗效。并且记录患者治疗后6个月内的复发情况,判断其远期临床疗效。结果龙胆泻肝汤与龙胆泻肝配方颗粒治疗湿热下注型生殖器疱疹的近期疗效与远期疗效均优于西药阿昔洛韦片,差异有统计学意义(P<0.05)。龙胆泻肝配方颗粒的疗效与传统汤药的疗效相当(P>0.05)。结论龙胆泻肝配方颗粒治疗湿热下注型生殖器疱疹有确切的临床疗效。

Objective To investigate the clinical curative effec for damp-heat genital herpes and compare the effect between Methods The 60 patients were randomly divided group treated with the granule, traditional Longdan into 3 groups Xiegan decoeti t of Longdan Xiegan granule the granule and Aciclovir. of Longdan Xiegan granule on group with the decoction and western medicine Aciclovir group with Aciclovir, 20 patients in each group. The integral of clinical symptoms, clinical efficient rate and the recurring rate respectively were observed before and after the treatment. Recurrence rate were recorded after the treatment in six months and the long-term effect was measured. Result The short-term and long-term curative effects of both the granule and the decoction were better than those of Aciclovir for the herpes. The ef- fects between the granule and the decoction were nearly same. Conclusion Longdan Xiegan granule is effective for the damp-heat genital herpes.