壮族高血压患者胰岛素水平与职业的关系

The relationship between insulin level and occupation in hypertensive

目的探讨壮族不同职业人群胰岛素基线及其与高血压的相互关系。方法选取教师、工人和农民原发性高血压患者301例，于早8～9点空腹测量血压，抽血检测空腹胰岛素和餐后胰岛素，并与相应职业的263例正常对照组比较。结果高血压教师组、工人组和农民组空腹胰岛素分别为15．92±5．94μIU／ml、8．90±3．56μIU／ml和7．07±2．07μIU／ml，教师组高于工人组（P〈0．01），工人组高于农民组（P〈0．01）；餐后胰岛素分别为57．83±47．99μIU／ml、47．98±33．13μIU／ml和30．95±13．37μIU／ml，教师组与工人组差异无统计学意义（P〉0．05），工人组高于农民组（P〈0．01）；在正常对照组中，教师组、工人组和农民组空腹胰岛素分别为11．31±6.81μIU／ml，7．32±4．11μIU／ml和5．15±3．27μIU／ml，教师组高于工人组（P〈0.01），工人组高于农民组（P〈0．01）；餐后胰岛素分别为40．55±33．76μIU／ml、36．84±28．53μIU／ml和26．33±15．41μIU／ml，教师组与工人组差异无统计学意义（P〉0．05），工人组高于农民组（P〈0．01）；在同职业组中，空腹或餐后胰岛素水平均表现为高血压组高于对照组（P〈0．05或〈0．01）。结论空腹胰岛素和餐后胰岛素水平在不同职业人群中是不一样的，从高到低依次为教师、工人和农民，这可能反映了体力劳动程度对胰岛素水平的影响；此外，职业相同者，高血压患者胰岛素水平高于血压正常者。

Objective To study the basicline of insulin and the mutual relationship between insulin and hypertention in zhuang with different occupations. Methods The fast blood pressure,fast insulin（FI）and postprandial insulin（PI）were measured at 8am to 9am in primary hypertensive group（n= 301）（from teacher,worker and farmer） , and compared with the control group（n= 263）. Results The hypertensive group： the FI were 5.92 ± 5.94 （μIU/ml, the same as follow,in teacher group）,8.90±3.56（in worker group）and 7.07±2.07（in farmer group） respectively ,and was significantly higher in teachers group than that in workers （ P 〈0.01）, and that in workers was higher than farmers（ P 〈0. 01）. And the PI were higher in workers compared with farmers（47.98±33.13 vs 30.95±13.37, P 〈0.01） ,while no significant difference was noted between teachers and workers（57.83±47.99 vs 47.98±33.13, P 〉0.05）. The control group：the FI were 11.31±6.81,7.32±4.11 and 5.15±3.27 respectively, which was lower in workers compared with teachers（ P 〈0.01） ,however was much higher compared with farmers（ P 〈0.01）. And the PI were higher in workers compared with farmers（36.84±28.53 vs 26.33±15.41, P 〈20. 01） ,but there was no significant difference between teachers and workers（40. 55 ± 33. 76 vs 36. 84 ± 28. 53, P 〉0. 05）. With regard to the same occupation, the FI or PI was much higher in hypertensive group than that in control group （ P 〈 0. 01 or 〈 0. 0 5 ）. Conclusion The order of FI and PI for high level to low level in different occupation is：teachers,workers,and farmers, which may show that level of insulin is influenced with different level of physical labor. Otherwise, when refer to the same occupation,the level of insulin is much higher in hypertensive than that in control group.