^(99m)Tc-MIBI乳腺癌阳性显像:鉴别乳腺肿物的良恶性及腋窝淋巴结转移的初步探讨

99mTc-MIBI Scintimammograph to Detect Primary Breast Cancer from Breast Tumor and Axillary Lymph Node Involvement

目的：探讨乳腺癌阳性显像的临床意义和对淋巴结转移的诊断价值。方法：静脉“弹丸”式注入９９ｍＴｃ－ＭＩＢＩ９２５ＭＰｑ，作１０分钟前位动态显像及前位、患侧侧位静态显像。结果：５８例共有６１个乳腺肿物，经病理证实３２个为恶性，２９个为良性。９９ｍＴｃ－ＭＩＢＩ乳腺癌阳性显像灵敏度为９０６％，特异性为９６５％。阳性预测率为９６７％，阴性预测率为９０３％；６例淋巴结转移，５例阳性。结论：９９ｍＴｃ－ＭＩＢＩ乳腺癌阳性显像可以成为鉴别乳腺肿瘤良恶性的方法之一，对腋窝淋巴结转移的检测亦具有应用价值。

Abstract:PURPOSE:TO discuss the clinical meaning of 99mTc-MIBI scintimammograph and evaluate the axillary lymph node involvement METHODS:99mTc-MIBI scintimammograph was performed in 58 patients with 61 breast masss.All was pathologically proved after opratiopn or fine-needle aspiration cytology.RESULT:32 of 61 breast lesions were breast cancer,among 29 were detected using 99mTc-MIBI.The other 29 were bening one,28 with negative result.The sensitivity and specificity was respectively 906% and 965% The positive and negative predictive value was respectively 967% and 903% 6 of 32 breast cancer was pathologically with metastatic axillary lymph nodes involvement,among 5 were detceted.CONCLUSION:99mTc-MIBI scintimammograph is a highly sensitive method in detection breast cancer.This study also show the potential value of this procedure to detect axillary lymph node involvement concomitant information.