摘要
通过对176个女性肺癌先证者核心家系和194个女性对照的核心家系资料分析。发现女性肺癌先证者的一级亲属(父母、同胞)患肺癌的危险性是对照一级亲属(父母、同胞)的1.67倍,且差异具有显著性。其中女性亲属患肺癌的危险性显著高于对照的女性亲属,OR值为2.81(P<0.01)。女性肺癌的遗传度为20.54%,遗传因素是女性肺癌的重要危险因素。女性肺癌先证者的女性亲属对肺癌的遗传易感性比男性亲属高。这些结果有助于全面阐明云南省宣威县女性肺癌高发的原因。
194 cases unclear families as a control were compared with 176 cases female lung cancer probands nuclear families.We found that the relatives (parents and siblings) of probands were 1.67 times greater risk of lung cancer than the controls relatives(parents and siblings),and the difference was statistically significant.The OR of lung cancer among female relatives was 2.81(P<001).The heritability of lung cancer was 20.54% in the women.Those results were helpful to explain the highest incidence among women in Xuan Wei County.
出处
《中国慢性病预防与控制》
CAS
1998年第1期5-7,共3页
Chinese Journal of Prevention and Control of Chronic Diseases