45例恶性肿瘤患者血液流变学指标检测与分析

Detection and analysis of hemorheological indicators in 45 patients with malignant tumor

目的探讨恶性肿瘤患者血液流变学指标的变化。方法对45例恶性肿瘤患者与35例健康人血液流变学指标进行检测并比较。结果男、女恶性肿瘤患者全血黏度、血浆黏度、纤维蛋白原、红细胞沉降率(下称血沉)和血沉K值结果均较健康对照组明显增高,差异有统计学意义(P<0.01);红细胞压积较健康对照组降低,差异有统计学意义(P<0.05)。结论恶性肿瘤患者血液流变学存在明显异常,呈高黏滞血症改变,通过血液流变学各指标的动态观察,对恶性肿瘤患者诊断、治疗及预后判断有一定的临床价值。

Objective To study the changes of hemorheological indicators in patients with malignant tumor. Methods The hemorheological indicators were measured in 45 patients with malignant tumor and 35 healthy adults. The results were compared. Results Compared with those in healthy control group, whole blood viscosity, plasma viscosity,profibrin,ESR, and ESR K value were significantly increased in malignant tumor group （P〈0. 01）, but hematocrit was decreased （P〈0.05）. Conclusion The malignant tumor patients display hyperviscosaemia. Dynamic observation of hemorheological indicators has certain clinical value in the diagnosis,therapy and prognosis evaluation of malignant tumors.