白血病患者化疗后应用白介素Ⅱ对T淋巴细胞亚群的影响

The inluence of using interleukin-Ⅱ to T lymphocyte subgroup after patient' chemotherapy

目的探讨白血病患者化疗后应用白介素II治疗对细胞免疫功能的影响及其临床意义。方法分为化疗加白介素II组(治疗组)和单纯化疗组(对照组),治疗组于化疗后毎天加用白介素II40万U静脉滴注,连用14d,检测化疗前及治疗后T淋巴细胞亚群的变化。结果治疗组化疗14d后CD3、CD4、CD56、CD4/CD8比值明显高于本组化疗前及对照组化疗后水平。结论化疗后应用白介素II能明显提高患者T淋巴细胞亚群的水平,对提高机体的免疫功能有积极的意义。

Objective To probe into the influence and the elineal signieanee of using interleukin-Ⅱ to T lymphocyte subgroup after patient＇ chemotherapy for leukmia patients. Methods Comparing with two groups： a treating group （ chemotheraphy with Interleukin-Ⅱ ） and a control group （ pure chemotherapy）. The treating group,after the chemotherapy,are dripped with interleukin-Ⅱ （400000 U） for 14 days. Then examine the T lym- phocyte change in pre-chemotherapy and post-chemotherapy. Results After 14 days, the radio of CD3 , CD4 CD8 ,CD56 ,CD4/CD8 is obviously higher than that of pre-ehemotherapy of the control group. Conclusion Using interleukin-11 can obviously raise the level of T lymphocyte and can raise the level of T lymphocyte and can raise the oranism immunologic function.