直肠癌根治术的远期疗效

Long-term results after radical resection in patients with rectal cancer

目的：分析我院直肠癌根治术后远期效果和影响手术疗效的各种因素。方法：收集我院１９６４年４月～１９８９年１２月根治性切除直肠癌６３８例资料。用生命表法计算生存率，生存曲线用Ｇｅｈａｎ方法作显著性检验。结果：全组手术死亡率０．８％，随访率９８．８％。术后５、１０、１５、２０、２５年生存率为５８．７％、４９．８％、４８．０％、４７．３％和４４．２％。结论：直肠癌术后生存率与年龄、肿瘤部位、大小、侵占肠腔周径、大体和组织学类型、淋巴结转移、病期等有关。其中，淋巴结转移和病期是影响术后生存率的最主要因素。

Purpose: To analyse the long-term results of radical operation for the patients with rectal cancer, and the factors affecting the operative results. Methods: The data of 638 patients with rectal cancer in our hospital from 1964 to 1989 were collected and analysed. The survival rates were calculated by the life table method, and the survival experiences were compared by the Gehan statistic. Results: The postoperative 5-,10-,15-,20-,and 25-year survival rates were 58.7%, 49.8%,48.0%,47.3%,and 44.2%, respectively. Conclusion: The study showed that the postoperative survival rates of rectal cancer related to age, tumor site, size, enviralement, gross and histological type, lymph node(s) metastasis and stage. Among them, lymph node(s) metastasis and stage were the most important factors.