摘要
1例18岁女性使用丙泊酚静脉全身麻醉行人工流产术。该妇女进入手术室前30min肌内注射阿托品0.5mg,进入手术室后BP116/68mmHg,HR70次/min,SPO297%。在缓慢静脉注射丙泊酚约50mg后,该妇女出现胸闷,随之烦躁不安,面色苍白,呼吸困难,前胸出现大片荨麻疹,BP50/30mmHg,HR138次/min,SPO285%。考虑为丙泊酚引起的过敏性休克,立即停用丙泊酚,给予肾上腺素、地塞米松、异丙嗪及多巴胺治疗,10min后症状好转。
An 18 year-old woman received general intravenous anesthesia with propofol for induced abortion. The woman received IM atropine 0.5 mg 30 minutes before being transferred to the operating room. Her blood pressure was 116/68 mmHg, her heart rate was 70 beats/min, and her SPO2 was 97% after she was transferred to the operating room. She developed chest distress followed by dysphoria, pallor, dyspnea and extensive urticaria on her chest after a slow IV injection of propofol about 50 rag. Her blood pressure was 50/30 mmHg, her heart rate was 138 beats/min and her SPO2 was 85%. Propofol-induced anaphylactic shock was suspected. Propofol was discontinued immediately. Adrenalin, dexamethasone, promethazine and dopamine were given. Her symptoms improved ten minutes later.
出处
《药物不良反应杂志》
2008年第6期439-439,共1页
Adverse Drug Reactions Journal
关键词
丙泊酚
过敏性休克
不良反应
propofol
anaphylactic shock
adverse reaction
