摘要
1例41岁女性因粘连性肠梗阻入院行回肠末段切除术。术后给予血凝酶1KU+0.9%氯化钠注射液20ml静脉注射,1次/2h,连用3次。前2次用药时患者无不良反应,第3次用药过程中,患者突然神志不清,叹息样呼吸,口唇青紫,面色苍白,双侧瞳孔散大,心跳骤停。立即停药,给予胸外心脏按压,面罩给氧,同时静脉注射利多卡因、肾上腺素和阿托品。抢救30min,患者心跳、呼吸恢复。
A 41-year-old woman with adhesive ileus underwent terminal ileum resection. The woman was given intravenous injection of hemocoagulase 1 KU dissolved in 20 ml of sodium chloride 0.9% after surgery, once every two hours for three times. No adverse reactions occurred after receiving the first and second dose of the medication. However, during the third infusion, the patient abruptly developed unconsciousness, sighing respiration, cyanosis of lips, pale face, bilateral mydriasis, and cardiac arrest. The infusion was stopped immediately. She underwent closed-chest cardiac message and oxygen with assisted mask ventilation. Lidocaine, adrenaline, and atropine were given intravenously. Thirty minutes later, her heart beat and respiration recovered.
出处
《药物不良反应杂志》
2008年第6期443-444,共2页
Adverse Drug Reactions Journal
关键词
血凝酶
过敏反应
心跳骤停
不良反应
hemoeoagulase
hypersensitivity reaction
cardiac arrest
adverse reaction
