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不同β受体阻滞剂对冠心病合并慢性心力衰竭患者心功能的影响

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摘要 目的:探讨卡维地洛﹑美托洛尔对冠心病合并慢性充血性心力衰竭患者心功能的影响。方法:将70例冠心病伴心力衰竭患者随机分为两组。在常规抗心力衰竭治疗基础上,卡维地洛组加服卡维地洛3.125mg,每日2次,渐加至25mg,每日2次,或最大耐受剂量。美托洛尔组加服酒石酸美托洛尔6.25mg,每日3次,渐加至50mg,每日2次,或最大耐受剂量。观察两组患者心功能改善情况、左心室射血分数(LVEF)、左心室舒张末内径(LVEDD)、6min步行距离。结果:治疗后两组患者的心功能改善明显,LVEF、6min步行距离均增加,LVEDD均缩小,卡维地洛组稍明显,但两组间比较差异无统计学意义。结论:卡维地洛和美托洛尔均有改善冠心病伴心力衰竭患者心功能的作用。
作者 徐斌 吴杰
出处 《交通医学》 2008年第6期656-657,共2页 Medical Journal of Communications
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