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Apelin-APJ系统与心血管疾病

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摘要 APJ是一种孤儿G蛋白偶联受体,自从其内源性配基Apelin被发现后,Apelin-APJ系统参与了广泛的生理过程,在心血管系统方面的效应如调节血压、增强心肌收缩力、调节水盐代谢平衡,从而参与心功能衰竭、心肌肥大、冠心病及糖尿病等疾病的发生和发展,Apelin-APJ系统有望成为临床上新的治疗靶点。
出处 《中国动脉硬化杂志》 CAS CSCD 2008年第11期912-914,共3页 Chinese Journal of Arteriosclerosis
基金 2006年自治Ⅰ类科研项目(2006027)
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