冠状动脉狭窄严重程度与冠心病危险因素的相关性分析

Relationship between the severity of the coronary artery stenosis and the cardiovascular risk factors

目的探讨冠状动脉狭窄的严重程度与心血管疾病的危险因素的关系。方法对2004年9月至2005年8月在本院行冠脉造影的140例患者的临床资料进行分析,分析年龄、性别、吸烟、血压、血脂、血糖及危险因素与冠脉狭窄程度的关系。对冠状动脉的狭窄程度进行定量Gensini评分。采用单因素和多因素方法分析。结果单因素分析示:在冠脉积分逐渐增高的四组中,单个危险因素和危险因素数目的百分率也都逐渐增高。多因素Logistic回归分析示:高脂血症为冠脉狭窄的最显著的独立相关危险因素。其他危险因素依次为吸烟、糖尿病、男性、高血压、老龄。结论高脂血症是冠脉造影诊断冠心病的最显著的独立相关危险因素。

Objective To evaluate the relationship between the severity of the coronary artery stenosis（CAS） and the cardio-vascular risk factors. Methods The clinical datum of 140 patients from the Sptember 2004 to August 2005 received coronary angiography were analysed and studied . We analysed the relationship between the cardiovascular risk factors such as age, gender smoking, blood pressure , blood glucose , blood lipidemia, the amounts of the risk factors and the severity of CAS. The severity of CAS was qualified in a Gensini score. Analyses were achieved by univariate and multivariate mellitus. Results ①Logistic regression analysis showed that in the four groups whose Gensini scores were increased the percents of the single risk factor and the percents of the amounts of the risk factors were enhanced gradually. ②Multiple regression analyses indicated that hyperchole sterolemia was the most prominent risk factor. There were other risk factors in order as smoking, diabete, male, hypertension and old. Conclusion Hyperchole sterolemia is the most prominent risk factor diagnosing the CHD by the coronary angiography.