摘要抗菌肽是20世纪70年代由瑞典科学家H G Boman首次发现,其具有优良的光谱抗菌性能,无残留,不会导致耐药菌株的出现,是目前抗生素类较有潜力的替代品。早在20世纪80年代,人们就已试图通过转基因等生物工程技术改良物种或大量表达该类物质,目前已有众多表达体系和转基因动植物研究成功,并有一些抗菌肽类药物投入临床使用。
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