矽肺大容量全肺灌洗治疗前后血液流变学观察

The Dynamic Observation of Hemorrheology in Patients with Silicosis Treated with Help of Whole-lung Lavage(WLL)

探讨血液流变学在评价大容量全肺灌洗（WLL）治疗矽肺疗效中的应用。对30例实施大容量全肺灌洗治疗的矽肺患者作了灌洗前后血液流变学的动态观察及肺功能测定、血气分析。结果：经大容量全肺灌洗治疗的矽肺患者由于肺通气功能的改善及动脉血氧分压（PaO2）的提高，其高粘滞血症、红细胞聚集、红细胞变形异常、Casson屈服应力增高状态有明显改善，各项指标均趋于正常。血液流变学的各项检查在评价大容量全肺灌洗治疗矽肺的疗效中具有重要作用。

Evaluating the clinic effect in treating the patients with silicosis by the help of WhL on application of hemorrheology. Determing the hemorrheology,lung function,blood gas analysis to 30 patients withsilicosis treated with WLL. The hyperviscosamia, erythrocyte aggregation, red blood cell deformability andcasson yield stress were greatly improved .and all of the data were normal. As of improving their capacity ofbreathing and the PaO2 by treating with WLL. It is important to evaluate the clinic in treating with the help ofWLL by determing the hemorrheology.