胎盘沙眼衣原体与母婴关系

Placental chlamydia trachornatis infection and puerperal neonate.

应用 PCR 检测方法,对535例妊娠晚期分娩产妇的胎盘组织进行沙眼衣原体(CT)检查,其中阴道分娩391例,剖宫产术144例,并对 CT 阳性与阴性者在足月低体重儿、产褥热、新生儿肺炎和新生儿黄疸等方面进行比较。结果:70例 CT 阳性,阳性率13.08%,其中阴道分娩 CT 阳性56例,阳性率14.32%,剖宫产术 CT 阳性14例,阳性率9.72%,两者无显著性差异(P>0.05)。CT 阳性者中足月低体重儿、产褥热、新生儿肺炎和新生儿黄疸发病率明显高于阴性者(P<0.05)。提示:分娩过程产道污染不是导致 CT 感染的唯一因素,部分胎盘在宫内已存在 CT 感染,CT 宫内感染与足月低体重儿、产褥热、新生儿肺炎及新生儿黄疸有关。

Objective: Study on the infectious channel of chlamydia trachomatis (CT) infection of the preg- nant woment and their babies,Methods: CT was detected in placenta tissue of 535 cases of third tri- master women (included 391 cases of vaginal deliv- ery and 144 cases of cesarean section) with PCR method.This study also compared the difference between positive cases and negative cases in low birth weight,puerperal infection,neonatal pneu- monia and neonatal jaundice.Results: 70% cases were positive in all cases,the positive rate was 13.08%.Among the positive cases,vaginal deliv- ery had 56 cases (14.32%) cesarean section had 14 cases (9.72%) there was no significant differ- ence between the two grou9ps.Low birth weight, ptierperal infection,neonatal pneumonia and neonatal jaundice in positive cases were significant- ly higher than that in negative cases.Conclusion: This result indicated that CT infection of the pla- centa was present before passing through the birth canal and not only due to contaminant during de- livery.