参芎葡萄糖注射液单独应用与配合使用治疗慢性肾脏病的疗效比较

Curative effect comparison of ShenXiong glucose injection in the treatment of Chronic Kidney Disease-Compared Compound preparation with inoculation fluid applies and the coordinate use

目的观察参芎葡萄糖注射液治疗慢性。肾脏病的临床疗效。方法将60例慢性肾脏病第三期的患者,随机分为①治疗组(30例),除给予常规治疗外,加用参芎葡萄糖注射液200ml,日一次静点;②对照组(30例),加用路路通注射液20 ml,日一次静点,4 w为一疗程。观察血尿素氮(BUN)和血清肌酐(SCr)的变化。结果治疗后两组各项检测指标均有不同程度好转,BUN和SCr均显著下降(P<0.01),但治疗组BUN和SCr降低程度明显高于对照组(P<0.05)。治疗组总有效率为83.3%,明显优于对照组60.0%(P<0.05)。结论参芎葡萄糖注射液能延缓慢性肾脏病的进展,配合使用明显优于单独应用。

Objective To evaluate the clinical efficacy of shenxiong glucose injection in the treatment of Chronic Kidney Disease（CKD）. Methods 60 patients with CKD in the third intention were divided into a treatment ground （n = 30） and a controlled group （ n = 30）. The treatment group received shenxiong glucose injection 100ml daily. 28 days for one course of treatment, the controlled group received Lulutong injection 20ml with 5% Glucose 150ml. The changes of serum BUN and SCr were observed. Results The serum BUN and SCr were significantly decreased in the two group after the treatment（P 〈 0. 01 ）and the levels of BUN and SCr were significantly lower in the treatment group than those in the controlled group （P 〈 0.05 ）. The total effective rates of the treatment group and controlled group were 83.3% and 60.0% respectively. There was a statistical difference between the two groups （P 〈 0. 05 ）. Conclusion shenxiong glucose injection is effective in the treatment of the CKD, Compound preparation is better than Unilateral preparation.