186例慢性萎缩性胃炎10年随访分析

A long- term outcome of 186 cases chronic atrophic gastritis about a 10- year follow- up study

目的：探讨慢性萎缩性胃炎（CAG）的转归，尤其是CAG伴肠上皮化生和不典型增生与胃癌的关系。方法：对186例经胃镜及病理诊断为CAG的患者进行10年随访．结果：5例逆转为慢性浅表性胃炎，52例有不同程度的减轻，33例萎缩范围与程度及肠上皮化生有不同程度的扩大与加重，3例癌变。结论：对慢性萎缩性胃炎特别是CAG伴肠上皮化生、不典型增生与HP感染者，应进行包括根除幽门螺旋杆菌在内的防治干预和定期随访。

Objective：To investigate the long-term outcome of chronic atrophic gastritis, and the relationship between CAG with intestinal metaplasia and dysplasia and gastric cancer. Methods：A follow up study was applied for the 186 cases with CAG; which were diagnosed with gastroscopy and pathological changes, the period was 10 years. Results： There were 5 in 186 cases reversed to be chronic superficial gastritis. The different alleviation was seen ill 52 of 186 cases. The areas of atropy of 33 in 186 cases enlarged in different degrees, and the degrees of atrophy and intestinal metaplasia of them increased to some extent. And there were only 3 in 186 cases that developed gastro - cancer finally. Conclusions： There is significance for the chronic atrophic gastritis, especially for those who companied with intestinal metaplasia, atropical,plasty and HP infection. Through a fixed period follow- up and by prevention and treatment, including eradication of HP infection.