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氯胺酮超前镇痛对上腹部手术后镇痛的影响 被引量:1

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摘要 目的:观察上腹部手术术前静脉应用小剂量氯胺酮对术后镇痛的影响。方法:选择60例择期上腹部手术病人,随机分为两组,每组30例。实验组在切皮前5min注入氯胺酮0.5mg/kg,对照组注入生理盐水。两组术后均采用曲马多行自控硬膜外镇痛。记录术后4,8,16,32,48h VAS评分,自控硬膜外镇痛首次触发时间,48h镇痛药液消耗量及不良反应。结果:实验组术后疼痛出现时间明显延长(P<0.05),术后8h及16h两组VAS评分有统计学意义(P<0.05),两组48h内曲马多消耗量有显著差别(P<0.05),两组不良反应无明显差异。结论:手术开始前应用小剂量氯胺酮具有超前镇痛作用,可加强曲马多术后镇痛的效果,减少曲马多消耗量。
出处 《护理实践与研究》 2009年第1期15-17,共3页 Nursing Practice and Research
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