无症状脑梗死的临床研究

Clinical study on the silent cerebral infarction

目的:了解无症状脑梗死的发生率、梗死部位及相关的危险因素。方法:2006年7月～2007年12月在干诊科住院及门诊体检的65岁以上老年患者214例,平均年龄为77.34岁,所有患者均无明确的神经系统病变,根据头部CT和(或)头部MRI检查,明确114例为无症状脑梗死,分析无症状脑梗死的部位和大小以及无症状脑梗死相关的危险因素。结果:114例确诊为无症状脑梗死的患者,梗死多发部位依次为基底节、侧脑室旁、深部脑白质、丘脑、脑干,病灶大小大多在5～15mm之间,多部位病灶的发生率占44.55%。结论:通过对老年无症状脑梗死患者的调查及危险因素的分析,发现年龄、高血压和糖尿病是无症状脑梗死的主要相关危险因素。

Objective： To investigate the incidence, the infarction position of silent cerebral infarction and its relevant risk factors. Methods： 214 patients older than 65 years （the average age is 77.34 years） were selected from the clinic physical examination and hospitalized patients from July 2006 to December 2007. All patients didn＇t have any explicit nerve system organic diseases. 114 patients were confirmed as silent cerebral infarction by using cranial CT and/or MRI. Then the position and area of silent cerebral infarction as well as its relevant factors were analyzed. Results： A total amount of 114 patients were diagnosed as silent cerebral infarction, the most frequent positions of infarction in turn was basal ganglion, lateral ventricle, deep white matter of brain, thalamus and brainstem. The majority of lesions sizes lied between 5-15 mm, and the incidence of multiple lesions were 44.55%. Conclusion： Age, hypertension and diabetes were found to be the significant factors for silent cerebral infarction by the investigation and analysis of old patients with silent cerebral infarction.