成人化脓性脑膜炎的临床表现与脑脊液细胞学分析

The clinical features and analysis of the cerebrospinal fluid of purulent meningitis in adult

目的探讨成人化脓性脑膜炎的临床特征及脑脊液细胞学的特点。方法回顾性分析采用头颅CT或MRI等检查，并经脑脊液细胞学、脑脊液及血培养检验证实的65例化脓性脑膜炎患者资料。结果行头颅CT或MRI检查并经脑脊液细胞学、脑脊液培养及血培养检验证实，被检测的65例患者确诊为化脓性脑膜炎。结论临床表现及典型的脑脊液细胞学改变仍然是化脑诊断的主要依据；早诊断，早治疗，足量，长疗程，选用易透过血脑屏障抗菌药是治疗的关键。

Objective To explore the clinical feature and characteristic of the cerebrospinal fluid of purulent meningitis in adult. Methods Analyzed retrospectively the data of 65 patrents with purulent meningitis. The following examinations were done respectively： Brain CT, MRI, cerebrospinal fluid, cerebrospinal fluid and blood cultures. Results The results suggested that the purulent meningitis was made a definite diagnosis based on the above examinations. Conclusion Our analyses suggested that clinical features and characteristic of the cerebrospinal fluid was main diagnostic criteria ; and the key of cure was that antimicrobials penetrated blood brain barrier and early diagnosis, treatment.