鸡大肠杆菌病的诊断及药物治疗试验

Diagnosis and Medication Test of Chicken E. coil

目的通过药物敏感性试验筛选对本地区大肠杆菌敏感药物进行治疗。方法根据临床诊断、微生物学和生化实验诊断大肠杆菌病;采用药敏试验测得的敏感药物阿米卡星、氟苯尼考、硫酸安普霉素、盐酸环丙沙星、硫酸庆大霉素、盐酸多西环素对试验动物进行分组用药。试验鸡700羽,设6个试验组,1个对照组,每组100只。结果在所选8种药物中,鸡大肠杆菌对硫酸安普霉素、氟苯尼考、阿米卡星、硫酸庆大霉素高度敏感;对盐酸多西环素、盐酸环丙沙星中度敏感,对硫酸链霉素和诺氟沙星耐药。结论应用筛选的敏感药物治疗锦州地区鸡大肠杆菌病效果良好。

Objective The objective was to screen sensitive drugs for E. coli in the local area through drug sensitivity test. Methods Colibacitlosis was diagnosed by clinical, microbiological diagnosis and biochemical tests, the sensitive drugs got by drug sensitivity tests including amikacin, florfenicol, apramycin sulfate, Ciprofloxacin, gentamicin sulfate, doxycycline hydrochloride were medicated to experimental animals which should be divided into groups. 700 chickens were divided into seven groups, six of which were test ones and one of which was the control group （ 100 chickens/group）. Results Of the eight chosen drugs, E. coli was hypersensitive to amikacin, florfenicol, apramycin sulfate, gentamicin sulfate and medium sensitive to doxycycline hydrochloride and Ciprofloxacin, insensitive to Streptomycin sulfate and Norfloxacin. Conclusions Treating the chicken colibacillosis by applying the sensitive drugs got good effects.