氧化应激、凋亡与肺气肿

Oxidative stress,apoptosis and emphysema

肺气肿发病机制不明，传统观点认为肺部炎症导致蛋白酶／抗蛋白酶失衡而致。现代研究表明，肺气肿患者中存在氧化应激水平增高和凋亡。氧化应激与凋亡关系密切，在肺气肿发病机制中起重要作用。

Pathogenesis of emphysema remains unkown. Traditional view shows that inflammation leads to protease-antiprotease imbalance. Modern research shows that increased levels of oxidative stress and apoptosis exist in emphysema patients. Oxidative stress and apoptosis are closely related and play an important role in the pathogenesis of emphysema.