摘要
心力衰竭是导致人类死亡的主要疾病之一,目前尚无有效的治愈方法。心力衰竭的发生有多种病因,但导致心力衰竭的基本病理变化是心肌细胞水肿、变性、坏死和纤维化,病理生理变化是心脏扩大、收缩力下降、每搏量和心排血量降低。发生这些变化的基础是体循环、脏器循环和微循环功能出现不同程度障碍,进而形成恶性循环最终导致心力衰竭的发生。基于此理论提出临床心衰治疗模式的转变和深思,目的是进一步提高心力衰竭疗效和改革医学教育模式。
Heart failure is an important disease causing people death. At present there is no good effective method to cure it. Many etiological factors can cause heart failure. But the basic pathologic changes of heart failure are myocardium edema, denaturation, putrescence and fibrosis. The main pathophysiological changes are heart expanding, contractive force descending, LVSV and cardiac output lowering. The foundation of that is the different dysfunction of body circulation, organ circulation and microcirculation. Thus vicious circle of those factors at last brings about heart failure. Basing on this theory the change of curing mode and recognition about heart failure is proposed. The aim is further to improve effectiveness of heart failure and to reform medical education pattern.
出处
《医学综述》
2009年第2期225-227,共3页
Medical Recapitulate
关键词
微循环障碍
心力衰竭
发病机制
Mierocirculation dysfunction
Heart failure
Pathogenesis