γ-干扰素雾化气溶胶辅助治疗复治菌阳肺结核疗效观察

Clinical Observation of γ-Interferon Adjunctive Therapy with Atomization Aerosol for Retreated Tuberculosis with Bacteria-positive

目的研究γ-干扰素辅助治疗复治菌阳肺结核的疗效。方法将70例复治菌阳肺结核患者随机分为两组，实验组（35例）应用γ-干扰素＋化疗药物，对照组（35例）只应用化疗药物。观察两个月后痰菌阴转、病变吸收情况。结果实验组患者在治疗后在痰菌阴转，肺部病灶吸收方面优干对照组．二者差异有统计学意义（P〈0．01）。结论经γ-干扰素雾化气溶胶辅助抗结核药物治疗后，复治菌阳肺结核患者在痰菌阴转及病灶吸收方面均明显优于单纯应用抗结核药物组。

Objective To study the effect of γ-interferon adjuvant therapy for re-treated tuberculosis patients with bacteria-positive. Methods 70 cases were divided into two groups, experimental group （ 35 cases） with the application of γ-interferon plus chemotherapy drug, while control group （35 cases） only with chemotherapy drug. The sputum conversion and absorption of pathological condition were observed after two months. Results Experimental group were better than control group in sputum convertion and absorption of pathological condition. There. are significant different between two groups. （ P 〈 0. 01 ）. Conclusion Adjuvant therapy with γ-interferon achieved better results than group only with antituberculosis drugs in sputum convertion and adsorption of pathological condition.