头孢曲松治疗小儿急性细菌性痢疾84例临床观察

A clinical investigation of treatment of acute bacillary dysentery with ceftriaxone in 84 children

目的 :评价头孢曲松对急性细菌性痢疾 (急性菌痢 )的治疗效果。方法 :采用双盲随机对照方法对 177例急性菌痢进行疗效观察 ,其中 84例使用头孢曲松作为观察组 ,93例使用其它抗菌药作为对照组。结果 :观察组 3日治愈率达 94 % ,明显高于对照组的 39% (P<0 .0 1) ,且在平均退热时间、粪镜检和粪培养阴转时间等方面均明显优于对照组。结论 :头孢曲松速效、高效 。

Objective:To evaluate the effectiveness of ceftriaxone in treating acute bacillary dysentery.Methods:177 cases with acute bacillary dysentery was randomly divided into two groups.84 cases as the investigating group were treated with ceftriaxone and 93 cases as the control group were treated with other antibiotics.Results:3 day cure rate in investigating group was 94%.but only 39% in control group( P <0 01).The investigating group also had superiorities in average time of temperature reducing and the time needed for negative stool microscopic examination and culture.Conclusion:Ceftriaxone is an ideal antibiotic for bacillary dysentery caused by multidrug resistant bacteria and the treatment is rapid and highly effective.