早发型重度子痫前期48例临床分析

A study of 48 cases of early onset severe preeclampsia

目的探讨早发型重度子痫前期的治疗和母儿结局。方法对我院2002年6月-2007年6月收治的经保守治疗的48例早发型重度子痫前期患者进行回顾性分析，根据发病孕周不同分成三组，即A组8例（24—27^＋6周），B组17例（28～31^＋6周），C组23例（32～33^＋6周）。结果三组病例并发症发生率无显著差异，但三组间围生儿死亡率及新生儿窒息率有显著差异。结论早发型重度子痫前期新生儿窒息和围生儿死亡率随发病孕周延长而降低，应严格选择病例进行期待治疗，并严密监测母胎情况，适时选择合适的终止妊娠方式。

Aim To study the treatment and the maternal and neonatal outcomes of early ohset severe preeclampsia. Methods A retrospective study was carried out on 48 patients with early onset severe preeclampsia. They were divided into three groups according to their onset gestation ages：group A（24 -27^＋6 weeks） ,group B（28 -31^＋6 weeks） and group C（32 -33^ ＋6 weeks）. Results For the rates of complications there were no statistical significant differences among these three groups. The neonatal asphyxia rate and perinatal infant mortality of these three groups declined with the postponement of gestation age, and there were statistical significant differences among these three groups. Conclusion The neonatal asphyxia rate and perinatal infant mortality of early onset severe preeclampsia declined with the postponement of pathogenic week of gestation. During the expectant treatment, the situation of maternity and fetus should be closely monitored and pregnancy termination should be decided at the proper time.