摘要
采用小剂量抗胸腺淋巴细胞球蛋白(ATG)对436例尸体肾移植术后病人进行排斥反应的预防。结果:发生急性排斥反应72例(16.51%),血肌酐在2d~10d恢复正常348例(79.82%),11d~32d62例(14.22%),并发感染18例(4.13%),摘除移植肾19例(4.36%),死亡12例(2.75%)。提示:肾移植术后早期应用小剂量ATG可预防排斥反应,降低CsA肾中毒。
Low dose antithymocyte globulin (ATG) was used to prevent the rejection in 436 patients with transplantation of kidney from the corpse.Results were that the rejection appeared in 72 patients (16.51%),blood creatinine returned to normal during 2 to 10 days in 348 patients (79.82%) and during 11 to 32 days in 62 patients (14.22%),and 12 died,suggesting that postoperative early application of low dose ATG may prevent the rejection,and the occurence of AR was lowered.