鼻塞持续气道正压给氧治疗新生儿呼吸窘迫综合征的临床观察

Clinical Study on the Effects of Nose-Stuffy CPAP on the Treatment in NRDS

目的观察鼻塞持续气道正压给氧(N-CPAP)对新生儿呼吸窘迫症(NRDS)的血气情况及临床疗效。方法将48例NRDS患儿分为治疗组和对照组,治疗组28例采用N-CPAP给氧治疗,对照组20例采用头罩吸氧,比较两组治疗前后血气及疗效。结果治疗组经N-CPAP治疗后PaO2和SaO2较治疗前明显升高(P<0.05,P<0.01),PaCO2较治疗前下降(P<0.05),pH无明显变化(P>0.05);对照组治疗前后各项血气指标也均有改善;治疗组氧疗后较对照组PaO2和SaO2升高,有统计学差异(P<0.05),而pH和PaCO2两组差异无显著意义(P>0.05);治疗组并发症低于对照组,显效率高于对照组,均无显著性差异(P<0.05)。结论N-CPAP是治疗NRDS患儿的有效方法,能纠正严重低氧血症,改善血气,提高疗效。

Objective To investigate the effects of N-CPAP on the blood gas and the treatment effects. Methods Devided 48 NRDS children into treatment and control group： 28 in treatment group were adopted N-CPAP and 20 in control group were treated with head-coveting oxygen absorption, then to compare the effects of two groups. Results Blood gas analysis, PaO2 and SaO2 in treatment group incresed dramatically （P 〈0.05, P 〈0.01）, and PaCO2 reduced （P〈0.05） while pH has no difference （ P 〉0.05） after treatment; meanwhile, compared with control group, the blood gas, the rate of complications and cure rate all have been improved. Conclusion N-CPAP is a effective method to treat NRDS, which could correct hypoxemia, improve gas blood and enhance the curative effects.