X刀治疗颅内占位性病变

X-knife radiosurgery treatment of intracranial lesion.

目的探讨立体定向放射外科治疗颅内占位性病变的疗效。方法采用立体定向等中心直线加速器治疗颅内不同的病变１２７例，等中心照射剂量为１５～３５Ｇｙ（平均２４５Ｇｙ），良性肿瘤周边剂量选取８０％等剂量线，恶性肿瘤选取９０％以上的等剂量线。结果８８例（６９３％）随访１个月至２年，其中病变消失３１例（３５２％），缩小３１例（３５２％），无变化２０例（２２７％），增大６例（６８％）。结论该技术治疗脑转移瘤效果最为满意，脑转移瘤在Ｘ刀治疗后结合全脑照射，肿瘤有效控制率达９２５％。

Objective To explore treatment of intracranial lesions with stereotactic radiosurgery. Methods To treat 127 patients with intracranial tumours using X-knife radiosurgery, 50%-80% isodose line was used to over treat benign tumours, 80%-90% isodose line used to treat the malignant ones while isocentre dose was 15-35 Gy(24.5Gy). Results Eighty eight patients with intracranial lesions were followed up by neurological images from 1 month to 2 years. Intracranial tumours of 31 cases (35.2%) were disapperaed , shrinked in 31 cases (35.2%), and unchanges in 20(22.7%), grownd in 6(6.8%). Conclusions Treatment efficacy of brain tumour metastasis is good using X-knife radiosurgery and whole brain radiogherapy, the efficacious control rate of tumor was 92.5%.