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药用蚯蚓纤溶酶的制备及其性质的研究 被引量:6

STUDIES ON THE PREPARATION AND CHARACTERIZATION OF THE MEDICINAL FIBRINOLYTIC ENZYME FROM EARTHWORM
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摘要 从爱胜蚓中制备药用纤溶酶,经工厂中试.收率为2.52~2.74%;纤溶活性为24333~26560mm2/mg;水解酪蛋白活性为598~640mU/mg。制备工艺重复性好,操作简易可行。另报道了该酶的一些生化特性和稳定性的研究结果。 The medicinal fibrinolytic enzyme from the earthworm (Eisenia Foetlide) was prepared by enlarged production. The results showed that the yield of the enzyme was 2.52-2.74%;the activity of fibrinolysis and hydrolysis casein was 24333-26560 mm2/mg and 598-640 mU/mg respectively. The re- peatability and yield were also estimated and we con- sider it might be a simple valid method for pharmaceu- tical production. In addition, this paper also reported some biochemical characterization and stability about the medicinal enzyme.
出处 《华西药学杂志》 CAS CSCD 北大核心 1998年第1期19-21,共3页 West China Journal of Pharmaceutical Sciences
关键词 药用蚯蚓纤溶酶 制备 生化特性 纤溶酶 蚯蚓 Medicinal fibrinolytic enzyme from earthworm Preparation Biochemical characterization
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  • 1路英华,金汝成,吴应文,孟雪琴.钜齿远蚓(Amynthas dancataa)纤溶酶的分离纯化及其若干性质[J]生物化学杂志,1988(02).
  • 2路英华,金汝成.蚯蚓纤溶酶的提取、性质鉴定和溶介血栓的研究[J]兰州大学学报,1986(01).

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