期刊文献+

糖尿病肾病病理与临床研究进展 被引量:16

原文传递
导出
摘要 足细胞损伤是糖尿病肾病发生发展的重要原因,足细胞损伤时足细胞表达Nephri。蛋白下调,足细胞裂孔膜完整性破坏致大量蛋白尿产生;经肾活检研究发现,糖尿病肾病的病理结构与临床表现有时不一致;有研究胰腺移植能使由糖尿病。肾病导致的肾小球、肾间质损害逆转,病理改变恢复。
出处 《国际泌尿系统杂志》 2009年第1期124-127,共4页 International Journal of Urology and Nephrology
关键词 糖尿病肾病
  • 相关文献

参考文献21

  • 1Fioretto P , Mauer M. Histopathology of diabetic nephropathy . Semin Nephrol ,2007,27 : 195 - 207.
  • 2Caramori , Michael. Diabetes and nephropathy. Renal immunology pathology ,2003,12:273 - 282.
  • 3刘志红,李世军,陈朝红,曾彩虹,张波,周虹,黎磊石.糖尿病肾病患者足细胞病变的临床病理特征[J].肾脏病与透析肾移植杂志,2003,12(2):144-148. 被引量:67
  • 4Sally M , Marshall. The podocyte: a potential therapeutic target in diabetic nephropathy. Current Pharmaleutical Design, 2007,13 : 271 - 272.
  • 5Gerth VE, zhou X. ,Vize PD. Nephrin expression and three -dimensional morphogenesis of the xenopus pronephrie glomus. Dev Dvn , 2005,233:1131 - 1139.
  • 6Shankland SJ. The podocyte,s response to injury: role in proteinuria and glomerulosclerosis . Kidney Int, 2006,69 : 131 - 137.
  • 7Rantanen M, Palmen T , Patari A , et al Nephropathy TRAP lack slit diaphragms and show fibrotic glomeruli and cystic tubular lesions. J Am Soc Nephrol,2002,13 (6) : 1586 - 1594.
  • 8Hodgkinson AD, Mitlwand BA, Demaine AG. Polymorphisms of the glucose transporter gene are associated with diabetic nephropathy . Kidney Int ,2001,59(3) :985.
  • 9Norby SM, Cosio FG. Thin basement membrane nephropathy associated with other glomerular disease. Seminars in Nephrology ,2005.25 : 270 - 275.
  • 10Kanavchi M Dohi K. Discordance between retinopathy and nephropathy in type 2 diabetes . Nephron,1998,2:171 - 174.

二级参考文献14

  • 1Hoshi S, Shu Y, Yoshida F et al. Podocyte injury promotes progressive nephropathy in Zucker diabetic fatty rats. Lab Invest,2002,82:25.
  • 2Tryggvason K, Wartiovaara J. Molecular basis of glomerular permselectivity. Curr Opin Nephrol Hypertens,2001,10:543.
  • 3Endlich K, Kriz W, Wltzgall R. Update in podocyte biology. Curr Opin Nephrol Hypertens,2001,10:331.
  • 4Mundel P, Shazkland S J. Podocyte biology and response to injury. J Am Soc Nephrol,2002,13:3005.
  • 5Steffes MW, Schmidt D, McCrery R et al. Glomerular cell number in normal subjects and in type 1 diabetic patients. Kidney Int, 2001,59:2104.
  • 6Pagtaluma ME, Miller PL, Jamping-Eagle S et al. Podocyte loss and progressive glomerular injury in type Ⅱ diabetes. J Clin Invest, 1997,90:342.
  • 7Lemley KV, Blouch K, Abdullah I et al. Glomerular permselectivity at the onset of nephropathy in type 2 diabetes mellitus. J Am Soc Nephrol,2000,11:2095.
  • 8Cruz MCI, ZiYadeh FN, Isono M et al. Effects of high glucose and TGF-β1 on the expression of collagen Ⅳ and vascular endothelial growth factor in mouse podocytes. Kidney Int,2002,62:901.
  • 9White K E, Bilous R W, Marshall S M et al.Podocyte number in normotensive type 1 diabetic patients with albuminuria. Diabetes,2002,51:3083.
  • 10nakamura T,UshiYama C,Suzuki S et al. Urinary excretion of podocytes in patients with diabetic nephropathy.Nephrol Dial Transplant, 2000,15:1379.

共引文献66

同被引文献121

引证文献16

二级引证文献127

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部