摘要
从云南美登木内生真菌Phomopsis species Lz42的琼脂平板发酵物中分离得到2个倍半萜和5个麦角甾醇类化合物(1~7),其中化合物1和2为新化合物.应用波谱技术确定其结构为4-Deacetyl-10-oxo-di-hydrobotrydial(1)和麦角甾-6,22-二烯-5α,8α-环二氧-3-甲酸酯(2).
Endophytes, commonly present in higher plants, are important sources of natural products with pharmaceutical potential. A new sesquiterpenoid, 4-deacetyl-10-oxo-dihydro-botrydial(1) , and a new sterol, 22E ,24R-5α, 8α-epidioxyergosta-6,22-dien-3β-formate (2) , were isolated from solid cultures of an endophytie fungal strain Phomopsis species Lz42, cultivated on Maytenus hookeri, together with five related known compounds, 4β-acetoxy-9β-10β-15α-trihydroxyprobotrydial (3), 22E, 24R-5α, 8α-epidioxyergosta-6,22-dien-3β- ol (4), ergosterol ( 5 ), 22E, 24R-ergosta-7,22-diene-3β, 5α, 6β-triol ( 6 ) and 22E, 24R-ergosta-7,22-diene- 3β,5α,6β,9α-tetraol(7). Their structures were identified by extensive spectroscopic, experiments especially 2D-NMR.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
2009年第1期78-81,共4页
Chemical Journal of Chinese Universities
基金
国家自然科学基金(批准号:30430020)
中国科学院基金(批准号:KSCX2-SW-313)资助