针刺外关穴中枢激活效应的PET脑功能成像研究

PET Cerebral Functional Imaging Study on Activation Effect of Brain with Needling in Waiguan (TE5)

目的运用PET脑功能成像技术,以18F-FDG为显影剂,以假针刺状态为对照,观察针刺健康青年志愿者外关穴后的脑中枢激活效应。方法12例健康志愿者随机分成两组,每组6例,分别施以右侧外关穴真针刺和假针刺,同时运用西门子公司ECATEXACTHR+PET进行脑部扫描。所得图像采用SPM2软件包进行处理和分析。结果与假针刺比较,外关穴真针刺激活的脑中枢主要有左侧颞叶(BA42)、颞上回(BA42)、岛叶(BA13)、小脑。结论针刺外关穴能够激活一定的脑部功能区,其治疗作用与中枢激活密切相关。

Objective PET cerebral functional imaging method, photographic developer ^18F- FDG and sham needling control group were applied in the experiment to study the activation effect in brain center of healthy volunteers who received needling in the Waiguan. Methods Twelve healthy volunteers were randomly divided into two equal groups, and received Waiguan needling and sham needling respectfully, both in the right hand. Meantime. PET（ ECAT EXACT HR, Siemens Co. ） was applied to scan the brain. Images obtained were processed and analyzed by SPM2 software. Results Compared to sham needling control group, brain areas such as left temporal lobe （ BA42 ）, gyrus temporalis superior （BA42）, insular lobe（ BA13 ）, and cerebellum in Waiguan true needling group were significantly activated. Conclusion Waiguan needling activates certain brain areas, which correlated closely to its therapeutic effect.