以父母身高中值修正的中国5城市儿童身高生长图表的制订

Growth charts for Chinese children's height of five cities allowing for height of parents

目的分析儿童身高与父母身高的关系，制订以父母身高中值（mid—parental height，MPH）修正的中国5城市儿童身高百分住数生长图表。方法研究广州、上海、温州、大连、石家庄13401名2—16岁正常儿童。以Box，Cox幂指数模型拟合儿童的年龄身高百分位数曲线；由线性函数拟合儿童身高与MPH回归方程。结果青春期前，儿童身高与MPH的相关系数为0．43～0．55；青春期时以骨龄分组的儿童身高与MPH的相关系数（0．43～0．63）与以生活年龄分组时相似。以生活年龄2～9岁，男骨龄10—16岁、女骨龄10-15岁分段计算了儿童身高Z分值（SDS）与MPH的回归方程。结论MPH修正的身高百分位数生长图表为矮身高儿童的临床鉴别诊断提供了参考。

Objective The correlations between heights of children and mid-parental height （ MPH）, and the average of two parent＇ s height were investigated and the growth charts of Chinese children＇ s height allowing for height of parents were presented. Methods The subjects were 13401 （ boys 6868, girls 6533 ） normal children aged 2 - 16 years, from middle and upper socio-economic classes of five cities in the south and north of China. The height centile curves of children were smoothing by BCPE model. The equations between child height SDS and MPH were fitted by linear regression. Results The correlations between heights of children and mid-parental height （MPH） are between 0. 43 and 0. 55 before adolescence, and in adolescence this holds generally for pairs of variables when the children were grouped based on skeletal ages. Hence, the regressive equations between child height SDS and MPH were fitted for the subsections of 2 - 9 years, skeletal age 10 - 16 in boys and 10 - 15 in girls, respectively. Conclusion The growth charts of Chinese children＇ s height allowing for height of parents are useful in differential diagnosis of short children, especially in genetic small stature.