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C反应蛋白与冠状动脉不稳定斑块的关系

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摘要 目的探讨血C反应蛋白(CRP)与冠状动脉不稳定斑块的相互关系。方法将57例急性冠脉综合征(ACS)患者分为非ST段抬高心肌梗死组(NSTEMI组)21例与不稳定型心绞痛组(UAP组)36例。对照组21例为稳定型心绞痛(SAP)患者。所有患者测定血CRP水平。通过冠状动脉造影检查,将冠状动脉罪犯血管病变斑块形态按照Ambrose分型分为Ⅰ-Ⅲ型,并与血CRP水平进行相关分析。结果(1)NSTEMI组和UAP组患者血CRP水平高于SAP组;(2)血CRP水平与冠状动脉Ambrose斑块形态分型有关,尤其是Ⅱ型不稳定斑块者明显增高,但与冠状动脉病变的狭窄程度无关。结论ACS组患者血CRP水平显著升高,并且可作为预测不稳定斑块的指标。血CRP水平也可以作为评判ACS预后的指标。
出处 《临床内科杂志》 CAS 2009年第1期60-61,共2页 Journal of Clinical Internal Medicine
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