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HIF-1活性调节及其在缺血后血管新生中的作用 被引量：14

Key regulators of HIF-1 and its action in angiogenesis after ischemia
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摘要 缺氧诱导因子-1(hypoxia-inducible factor-1,HIF-1)是一种由α亚基和β亚基组成的异源二聚体。该文对HIF-1活性表达及其在缺血/缺氧诱发的血管新生中的重要作用做了简要综述。 Hypoxia-inducible factor-1 （ HIF-1 ） is a heterodimer of an O2-rugulated αsubunit and a constitutively expressed βsubunit. The article reviews the active expression of HIF-1 and its important role in angiogenesis induced by tissue hypoxia/ischemia.
作者 李玉娟 刘建勋
机构地区 中国中医科学院西苑医院实验研究中心
出处 《中国药理学通报》 CAS CSCD 北大核心 2009年第1期19-20,共2页 Chinese Pharmacological Bulletin
关键词 缺氧诱导因子-1 缺氧/缺血 血管新生 HIF-1 hypoxia/ischemia angiogenesis
分类号 R-05 [医药卫生] R322.12 [医药卫生—人体解剖和组织胚胎学]
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参考文献22

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二级参考文献23

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中国药理学通报
2009年 第1期

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