颅内海绵状血管瘤的临床特征与显微外科治疗

Clinical features and microsurgicai treatment of intracranial cavernous angiomas

目的探讨颅内海绵状血管瘤的临床特征、影像学特点和显微外科手术治疗方法。方法总结分析广州医学院第二附属医院神经外科自1998年1月至2008年6月收治的189例颅内海绵状血管瘤患者的临床表现、神经影像学特征及显微外科手术治疗方法等资料。结果183例颅内海绵状血管瘤位于脑实质内，以头痛、癫痫及出血为主要临床表现。均全切除病灶：6例位于脑外中颅窝底区，其中全切除病灶5例，病灶活检1例。结论显微外科手术治疗颅内海绵状血管瘤是一种安全和有效的方法，其疗效满意。

Objective To investigate the clinical and neuroimaging features and microsurgical approaches of intracranial cavernous angiomas （CA）. Methods The clinical and neuroimaging features and microsurgical approaches were analyzed retrospectively in 189 cases of intracranial CA. Results Of the 189 cases, 183 presented with CA in the cerebral parenchyma and clinical manifestations including predominantly headache, epilepsy, and hemorrhage, and were managed by radical resection of the CA. The other 6 cases showed intracranial CA in the middle cranial fossa, for which radical CA resection was performed in 5 cases and biopsy in 1 case. Conclusion Microsurgeries are safe and effective for treatment of intraeranial CA and may achieve good clinical outcomes.