期刊文献+

Survivin及p16在非小细胞肺癌中的表达与相关性 被引量:2

Expression and relationship of Survivin and p16 in non-small cell lung cancer
下载PDF
导出
摘要 Survivin是迄今发现的作用最强的凋亡抑制因子,p16是细胞周期蛋白依赖性激酶的抑制因子。Survivin和p16对非小细胞肺癌的临床诊断、治疗和预后有一定的指导意思。本文综述survivin及p16在非小细胞肺癌中的表达意义与相关性。 Survivin is considered as the strongest inhibitor of apoptosis ( IAP ) at present, p16 is a inhibitor factor of cyclin- dependent kinases (CDKs). Survivin and p16 have some instructive implications for clinical diagnosis, treatments and prognosis of non- small cell lung cancer(NSCLC) . This review analyzes the expression and relationship of survivin and p16 in non - small cell lung cancer.
出处 《现代肿瘤医学》 CAS 2009年第1期129-131,共3页 Journal of Modern Oncology
关键词 Survivn P16 非小细胞肺癌 相关性 Survivn p16 NSCLC relationship
  • 相关文献

参考文献23

  • 1Oeonnor DS, Schehner JS, Adida C, et al. Control of apoptosis during angiogenesis by survivin express in endothelial cell[J].Am J Pathol, 2000,156 (2) : 393.
  • 2Papapetropoulos A, Fulton D, Mubboubi K, et al. Angiopoietin - 1 inhibits endothelial cell [Jl. J Biol Chem,2000,275(13) :9102.
  • 3Hirokazu O, HitoshiT, Hideyasu O, et al. Phosphatidylinositol - 3 Kinase/Akt regulates angiotension Ⅱ induced inhibition of apoptosis in microvascular endothelial cells by governing survivin expression and suppression of caspase - 3 active circ[J].2004,94:785.
  • 4Kren L, Brazdil J, Hermanova M , et al. Prognostic significance of anti apoptosis proteins survivin and bcl - 2 in non - small cell lung carcinomas: a clinieopathologic study of 102 cases[ J]. Appt Immunohistochem Mol Morphol, 2004,12:44 - 49.
  • 5Monzo M, Rosell R, Felip E, et al. A novel anti apoptosis gene : Re - expression of survivin messenger RNA as a prognosis marker in non small cell lung cancers[J]. J Clin Oncol, 1999,17:2100 - 2104.
  • 6Falleni M , Pellegrini C, Marchetti A, et al. Survivin gene expression in early - stage non small cell lung cancer[ J]. J Pathol,2003, 200:620 - 626.
  • 7Ikehara M , Oshita F, Kameda Y,et al. Expression of survivin correlated with vessel invasion is a marker of poor prognosis in small adenocarcinoma of the lung[ J]. Oncol Rep ,2002,9,835 - 838.
  • 8陶琳,姚峰,李华,余峰,王敏,刘铭球.survivin基因表达与非小细胞肺癌发生发展的关系[J].中国肺癌杂志,2003,6(4):275-277. 被引量:12
  • 9Vischioni B, van der Valk P, Span SW , et al. Nuclear localization of survivin is a positive prognostic factor for survival in advanced non - small cell lung cancer [ J ]. Ann Oncol, 2004, 15 : 1654 - 1660.
  • 10Shen C, Buck A, Polat B, et al. Triplex - forming oligodeoxynucleotides targeting survivin inhibit proliferation and induce apoptosis of human lung carcinoma ceils[ J]. Cancer Gene Ther,2003,10: 403 -410.

二级参考文献36

  • 1[7]Andrade F, Roy S, Nicholson D, et al. Granzyme B directly and efficiently cleaves several downstreem caspase substrates: implications for CTL-induced apoptosis. Immunity,1998,8(4)∶451-460.
  • 2[8]Sarela AI, Macadam RC, Farmery SM, et al. Expression of the antiapoptosis gene, survivin, predicts death from recurrent colorectal carcinoma. Gut,2000,46(5)∶645-650.
  • 3[10]Adida C, Crotty PL, McGrath J, et al. Developmentally regulated expression of the novel cancer anti-apoptosis gene survivin in human and mouse differentiation. Am J Pathol,1998,152(1)∶43-49.
  • 4[1]Ambrosini G, Adida C, Altieri DC. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat Med,1997,3(8)∶917-921.
  • 5[2]Grossman D, McNiff JM, Li F, et al. Expression of the apoptosis inhibitor, survivin, in nonmelanoma skin cancer and gene targeting in a keratinocyte cell line. Lab Invest,1999,79(9)∶1121-1126.
  • 6[3]Tanaka K, Iwamoto S, Gon G, et al. Expression of survivin and its relationship to loss of apoptosis in breast carcinomas. Clin Cancer Res,2000,6(1)∶127-134.
  • 7[5]Keer JFR, Winterford CM, Harman BV. Apoptosis, its significance in carcinoma and carcinoma therapy. Carcinoma,1994,73(3)∶2013-2017.
  • 8[6]LaCasse EC, Baird S, Korneluk RG, et al. The inhibitors of apoptosis (IAPs) and their emerging role in cancer. Oncogene,1998,17(25)∶3247-3259.
  • 9AMBROSINI G,ADIDA C,ALTIERI D C.A novel anti-apoptosis gene,survivin,expressed in cancer and lymphoma[J].Nat Med,1997,3(8):917-921.
  • 10REKER S,BECKER J C,SVANE I M,et al.HLA-B35-restricted immune responses against survivin in cancer patients[J].Int J Cancer,2004,108(6):937 -941.

共引文献20

同被引文献29

引证文献2

二级引证文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部