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内皮素-1促肿瘤血管新生机制 被引量：8

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摘要 内皮素(ET)是一种由21个氨基酸组成的生物活性肽,有3种异构体(ET-1,ET-2,ET-3),目前研究最多也最清楚的是ET-1,在正常组织中它通过与其受体(ETR)发挥强大的缩血管及促有丝分裂作用。近年的研究证实,ET-1及ETR在多种肿瘤组织中分泌和表达,并起到促进肿瘤组织血管新生的作用。
作者 贾刚 张为民
机构地区 广州军区总医院肿瘤科
出处 《现代肿瘤医学》 CAS 2009年第1期165-168,共4页 Journal of Modern Oncology
基金 广东自然科学基金资助项目(项目编号:04101965) 广州市科技攻关项目(项目编号:2005Z3-E0051)
关键词 内皮素 血管内皮生长因子 血管新生 肿瘤
分类号 R730.3 [医药卫生—肿瘤]
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参考文献24

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二级参考文献65

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现代肿瘤医学
2009年 第1期

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