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联合活化重组Ⅶ因子和腹腔填塞在损害控制中的应用 被引量:4

Application of recombinant activated factor Ⅶ and abdominal packing on damage control surgery
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摘要 目的应用损害控制理念,观察联合应用活化重组Ⅶ因子与腹腔填塞对腹腔大出血的临床效果。方法2007年1月~2008年6月收治8例肠瘘合并腹腔大出血病人,均于术前推注50μg/kg活化重组Ⅶ因子,术中给予纱布填塞止血。结果8例病人均成功止血,2例最终因感染导致MODS而死亡,其余6例治愈。结论应用损害控制理念,联合应用活化重组Ⅶ因子与腹腔填塞是处理肠瘘合并大出血的有效治疗方式。 Objective To observe the effect of recombinant activated factor VII and abdominal packing in treating damage control surgery. Methods Eight patients with abdominal hemorrhea due to intestinal fistula were studied prospectively from January 2007 to June 2008. There were 7 male and 1 female. The mean age was ( 34.2 -+ 16.1) years old (23-60 years old). Recombinant activated factor Ⅶ(50μg/kg) was administered by intrave- nous injection 10 minutes before operation, and abdominal packing was administrated. Results Bleeding was successfully stopped in 8 patients. At the end, six patients survived, and the other two patients died because of MODS. Conclusion Damage control surgery with abdominal packing and recombinant activated factor VII is an effective nrocedure for hemorrhea combined with intestinal fistula.
出处 《创伤外科杂志》 2009年第1期15-17,共3页 Journal of Traumatic Surgery
基金 全军医学科学技术研究"十一五"计划专项课题资助(06Z017)
关键词 损害控制 腹腔出血 纱布 肠瘘 活化重组Ⅶ因子 damage control surgery abdominal hemorrhea gauze intestinal fistula recombinant activated factor Ⅶ
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参考文献9

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二级参考文献4

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