勃脉力A对2型糖尿病患者糖代谢的影响

The Influence of Plasma Lyte A on Glycometabolism in Type 2 Diabetic Patients during the Operation

目的比较两种不同晶体液对糖尿病患者手术中糖代谢的影响,从而选择最适合糖尿病患者手术中输注的晶体液。方法开腹胃肠道手术的患者40例,其中20例为2型糖尿病患者(D组);其余20例患者为非糖尿病患者(N组)。每组患者再随机分为两组,手术中分别输注乳酸钠林格注射液(L)和勃脉力A(A),分别为D-L组、D-A组、N-L组和N-A组。进行手术前和术后的动脉血气分析、血糖及血乳酸浓度的测定。结果D组患者两时相血糖浓度明显高于N组,术后输注乳酸林格液的两组患者血乳酸浓度均超过正常范围;除N-A组外的3组患者术后血乳酸浓度较术前均有显著性升高。结论勃脉力A对糖尿病患者是更加安全有效的手术中输注液体。

Objective To compare the effects of the two kinds of crystalloid solutions on glycometabolism in type 2 diabetic patients during the operation for the sclestion of the most suitable crystalloid solution. Methods In the forty scheduled gastrointestinal operation patients,there were twenty （D -group） type 2 diabetic patients and the others （N -group） were non -diabetic patients. Each of the two groups were randomly divided into two groups according to infusing different erystalloid solutions： lactated Ringer＇ s solution （L group） , Plasma Lyte A （A group）. So the patients were divided into D -L group, D -A group, N -Lgroup, N -A group. The blood glucose con- centration,the blood lactate concentration and artery blood gas analysis before operation （T0） and at the end of operation（T1）were mea ured . Results The blood glucose concentrations had significant increase at the end of operations,and the blood glucose concentrations of D group were higher than that of N group at T0 and T1. The lactate concentrations before operation were normal in all the patients, but the lactate concentrations were over the normal limits after infusing lactated Ringer＇ s solution and remained normal after infusing Plasma Lyte A. The lactate concentrations had significant increase in the other three groups except N - A group. Conclusion Plasma Lyte A is the more safe and efficient erystalloid solution for diabetic patients during the operation.