摘要
目的:评价塞克硝唑片治疗牙周炎的疗效和安全性。方法:61例牙周炎患者,采用多中心、随机、双盲、平行对照试验设计,比较试验组(塞克硝唑片,n=33)与对照组(替硝唑片,n=28)的临床疗效和安全性。结果:试验组与对照组治疗牙周炎的有效率分别为15.2%、14.3%(P>0.05);2组安全性皆很好,无显著性差异(P>0.05)。结论:塞克硝唑片治疗牙周炎疗效与替硝唑相当,安全。
OBJECTIVE： To evaluate the efficacy and safety of Secnidazole in patients with periodontitis. METHODS： This study was a multicenter, randomized, double- blind, parallel -controlled trial in which 33 periodontitis cases were treated by Secnidazole tablets （trial group）, and 28 by Tinidazole tablets （control group） . RESULTS： There were significant differences between the trial group and the control group in effective rate （15.2% versus 14.3% ） （P 〉0.05） . Nor were there significant differences between the two groups in safety. CONCLUSION： The therapeutic effect and safety of Secnidazole is similar to Tinidazole in patients with periodontitis.
出处
《中国药房》
CAS
CSCD
北大核心
2009年第2期131-133,共3页
China Pharmacy
关键词
塞克硝唑
牙周炎
厌氧菌
Secnidazole
Periodontitis
Anaerobic
