电针对脑血栓患者TXB_2、PGF_(1α)的影响与其基础状态的相关关系

THE Correlation between the Influence of Electroacupuncture on TXB_2 and PGF_(1α), and the Basic Condition in Cerebral Embolism Patients

目的探索针刺效应的强弱与机能状态之间的数量关系,分析针刺效应产生的规律性。方法以30例脑血栓患者为观察对象进行电针治疗,辰时和未时各治疗15例。主穴取患侧足三里、丰隆、三阴交、太溪、曲池、内关、合谷。配穴根据病位不同灵活取用。进针得气后接G6805治疗仪30min。每天治疗1次,连续治疗5次为1个疗程,治疗3个疗程后进行总结。所有患者在针刺前一天8:00-8:10和针刺3个疗程后次日8:00-8:10各抽取静脉血5mL,离心后分离血清并超低温冷冻保存备检TXB2、PGF1。结果电针治疗3个疗程后本组患者的TXB2、PGF1、TXB2/PGF1都能够获得明显的改善,而且电针疗法对TXB2、PGF1、TXB2/PGF1的改善程度均与针刺之前TXB2、PGF1、TXB2/PGF1的基础水平具有十分密切的直线数量关系,三者的相关系数分别为r=0.733>r0.01(28),P<0.01;r=0.544>r0.01(28),P<0.01;r=0.852>r0.01(28),P<0.01。结论在一定范围之内,机能状态偏离正常水平越明显,针刺调节效应也就越显著。

Objective To explore the quantitative relationship between acupuncture effect and functional status and analyze the law of producing an acupuncture effect. Methods Thirty cerebral embolism patients made up the subjects. They received electroacupuncture, with 15 cases treated in the morning and 15 cases treated in the afternoon. The main points selected were Zusanli（ST36）, Fenglong（ST40）, Sanyinjiao（SP6）, Taixi（KI3）, Quchi（LI11）, Neiguan（PC6） and Hegu（LI4） on the affected side. The adjunct points were selected according to different pathological positions. The needles were connected with a G6805 Multi-Purpose Health Device. Treatment was administered 30 min once daily, 5 times as a course. A summary was made after 3 courses of treatment. Venous blood was taken at 8：00-8：10 on the day before acupuncture and on the second day after 3 treatments. Serum was separated by centrifugation and stored under ultra low temperature refrigeration for measurement of TXB2 and PGF1α Results TXB2, PGF1α and TXB2/PGF1α improved in all the patients after 3 courses of electroacupuncture treatment. The degrees of improvements in TXB2, PG1α and TXB2/PGF1α had linearly quantitative relations with the pretreatment basic levels of.them. The correlation coefficients of the three were r=0.733〉r0.01 （28）, P〈0.01; r=0.544〉r0.01 （28）, P〈0.01; r=0.852〉r0.01（28）, P〈0.01. Conclusion In a certain range, the more obviously the functional status deviates from a normal level, the more marked regulating effect acupuncture produces.