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瘦素及其受体在子宫内膜异位症中的表达 被引量:1

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摘要 目的探讨瘦素及其受体在子宫内膜异位症(endometriosis,EM)发病中的作用。方法采用放射免疫法和免疫组织化学法检测30例EM患者和30例非EM妇女(对照组)体内瘦素及其受体的表达情况。结果EM患者血清瘦素水平与对照组无明显差异。瘦素在EM患者在位和异位内膜组织中的表达均明显低于对照组(P1〈0.01;P2〈0.05),而在位、异位内膜间无明显差异;瘦素受体在EM患者在位内膜中的表达低于对照组(P=0.05),而EM患者异位内膜与对照组,以及EM患者在位、异位内膜间瘦素受体表达无明显差异。结论EM患者在位内膜组织中瘦素及其受体表达的降低,可能促进了EM的发病。
出处 《河北医科大学学报》 CAS 2009年第1期59-61,共3页 Journal of Hebei Medical University
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共引文献4

同被引文献10

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